2-Morpholinecarbonitrile, 4-(phenylmethyl)-

2-Morpholinecarbonitrile, 4-(phenylmethyl)- - Names and Identifiers

Name	4-Benzylmorpholine-2-carbonitrile
Synonyms	2-Cyano-4-benzylmorpholine 4-Benzylmorpholine-2-carbonitrile 4-BENZYLMORPHOLINE-2-CARBONITRILE 4-Benzyl-2-Morpholinecarbonitrile 4-(Phenylmethyl)-2-morpholinecarbonitrile 2-Morpholinecarbonitrile, 4-(phenylmethyl)-
CAS	126645-52-1
InChI	InChI=1/C12H14N2O/c13-8-12-10-14(6-7-15-12)9-11-4-2-1-3-5-11/h1-5,12H,6-7,9-10H2

2-Morpholinecarbonitrile, 4-(phenylmethyl)- - Physico-chemical Properties

Molecular Formula	C12H14N2O
Molar Mass	202.25
Density	1.14
Melting Point	161.3℃
Boling Point	343.1±42.0 °C(Predicted)
Flash Point	161.3°C
Solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
Vapor Presure	7.2E-05mmHg at 25°C
Appearance	Oil
Color	vColourless
pKa	4.89±0.10(Predicted)
Storage Condition	Refrigerator
Refractive Index	1.568
MDL	MFCD08751344

2-Morpholinecarbonitrile, 4-(phenylmethyl)- - Risk and Safety

Hazard Symbols	T - Toxic
Risk Codes	25 - Toxic if swallowed
Safety Description	45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany	3

2-Morpholinecarbonitrile, 4-(phenylmethyl)- - Reference Information

use

4-benzylmorpholin-2-methanonitrile is used as an intermediate in medicine and chemical industry. Morpholine compounds are widely found in natural products and have strong biological activity. They are the pharmacophore of many drugs. The biological activity test results of the synthesized morpholine derivatives show that these derivatives have pharmacological activities such as lowering cholesterol, anti-hyperlipidemia, treating arteriosclerosis and anti-inflammatory.

preparation

the target compound 4-benzyl morpholine -2-nitrile can be prepared by benzyl chloride reaction with morpholine -2-nitrile as the starting material or cyanide prepared from 4-benzyl morpholine -2-formaldehyde as the starting material. The synthesis reaction formula of 4-benzylmorpholine-2-methylonitrile is as follows: fig. 1 the synthesis reaction formula of 4-benzylmorpholine-2-methylonitrile

Last Update：2024-04-09 21:11:58